FREE US Shipping on Orders Over $85

Transino II 240 tablets Melasma Treatment


General Information on Japanese Transino II Tablets with Tranexamic Acid for Skin Whitening

  • Package detail: 240 tablets
  • Manufacturer: Daiichi Sankyo Healthcare Co., Ltd., Japan
  • Active ingredients: Tranexamic Acid, L-Cysteine, Vitamin C
  • Medical effect: 2-month course noticeably lightens age spots caused by solar insolation and age-related skin changes, evens out facial tone, and brightens the skin.

Contraindications and Precautions: Transino II tablets are strictly prohibited for the following categories of people:

  • Patients undergoing hemodialysis treatment
  • Patients with renal failure
  • Patients taking medications that include tranexamic acid
  • Patients with subarachnoid hemorrhage
  • Patients with thrombophilic conditions
  • Persons with hypersensitivity to any of the components of the tablets
  • Persons under 15 and over 55 years old
  • Pregnant and breastfeeding women

Dosage and Administration of Transino II Tablets with Tranexamic Acid for Skin Whitening from Japan:

  • Take 2 tablets a day after meals with water.
  • After completing the 2-month course, take a break of at least 2 months before the next course.

Effectiveness of Japanese Transino II Tablets with Tranexamic Acid for Skin Whitening:

  • Transino II tablets are effective for lightening hyperpigmentation caused by age-related changes and exposure to direct sunlight.
  • Studies show that tranexamic acid is particularly effective against hyperpigmentation caused by ultraviolet radiation (Bahareh Ebrahimi, Farahnaz Fatemi Naeini. Topical tranexamic acid as a promising treatment for melasma. Journal of Research in Medical Sciences, 2014 Aug; 19(8): 753–757).
  • L-cysteine ​​exerts antioxidant activity, inhibiting the effect of reactive oxygen species on melanocytes.
  • Vitamin C blocks the synthesis of the tyrosinase enzyme, helping prevent the appearance of melanin.
  • The combined action of the three active components can lighten existing spots, prevent the appearance of new spots, and improve overall complexion, resulting in brighter and more even skin.


  1. Tranexamic Acid:
    • Tranexamic acid is a synthetic derivative of the amino acid lysine.
    • It is known for its antifibrinolytic properties, which means it helps to prevent the breakdown of blood clots.
    • In the context of skin care, tranexamic acid has been found to be effective in treating hyperpigmentation, particularly melasma, which is a common skin condition characterized by dark patches on the face.
    • Studies have shown that tranexamic acid can inhibit the production and transfer of melanin, the pigment responsible for skin color, thereby reducing the appearance of dark spots and improving skin tone.
  2. L-Cysteine:
    • L-Cysteine is a naturally occurring amino acid that plays a crucial role in the synthesis of proteins and antioxidants in the body.
    • It acts as a precursor to glutathione, one of the most potent antioxidants in the skin.
    • As an antioxidant, L-cysteine helps to neutralize free radicals and oxidative stress, which can contribute to skin aging and hyperpigmentation.
    • By inhibiting the effect of reactive oxygen species on melanocytes (cells responsible for producing melanin), L-cysteine helps to reduce the formation of melanin and can assist in lightening dark spots.
  3. Vitamin C:
    • Vitamin C, also known as ascorbic acid, is a water-soluble vitamin with powerful antioxidant properties.
    • It plays a critical role in collagen synthesis, promoting skin elasticity and firmness.
    • In the context of skin whitening, vitamin C inhibits the activity of the enzyme tyrosinase, which is involved in melanin production.
    • By blocking tyrosinase, vitamin C helps to reduce the formation of melanin, leading to a brighter and more even complexion.


  • Main ingredients T.X.A: 750mg
  • L-Cysteine: 240mg
  • Ascorbic Acid (vitamin C): 300mg
  • Pyridoxine Hydrochloride (vitamin B6): 6mg
  • Calcium Pantothenate: 24mg

Combining these active ingredients in Transino II tablets provides a comprehensive approach to skin whitening and the treatment of hyperpigmentation. The synergy between tranexamic acid, L-cysteine, and vitamin C helps to address various factors contributing to dark spots and uneven skin tone, resulting in a more radiant and clearer complexion. As with any skincare product, it is essential to follow the recommended dosage and consult a healthcare professional if you have any specific concerns or medical conditions.